Ford E-Series (E-350, E-450) Fuse Box Diagram and Location (2021-2025)

The fourth-generation Ford E-Series (Econoline, E-350, E-450), after its fourth refresh, has been available from 2021 to 2025. Known for its durability, versatility, and reliability, the E-Series remains a top choice for commercial fleets, shuttle services, and cargo transport.

In this article, you will find fuse box diagrams for Ford E-Series models produced between 2021 and 2025, covering years 2021, 2022, 2023, 2024, and 2025. These diagrams provide crucial insights into the fuse layout, helping fleet operators, mechanics, and technicians locate and understand the function of each fuse and relay.

What’s Included:

  • Fuse Box Diagrams – Clear and detailed visuals to help identify fuses, relays, and circuit breakers.
  • Fuse Panel Locations – Step-by-step guidance on where to find the fuse panels inside the Ford E-Series.
  • Fuse Assignments – Comprehensive descriptions of each fuse and relay function for accurate diagnostics and troubleshooting.

Whether you’re searching for the fuse panel layout, replacing a blown fuse, or diagnosing an electrical issue, this guide is an essential resource. It ensures that your Ford E-Series’ electrical system remains functional and reliable for heavy-duty commercial use, passenger transport, and cargo hauling.

Keep your Ford E-Series (2021–2025) running efficiently with this detailed fuse box, fuse panel, and relay guide!

Fuse Box Locations

Passenger Compartment

The fuse panel is located to the left-hand side of the brake pedal and is mounted on the lower left-hand cowl panel. Remove the fuse panel cover to access the fuses.

Engine Compartment

Fuse Box Diagrams

Passenger Compartment

Assignment of the fuses in the instrument panel (2021-2025)

№RatingProtected Component
1—Not used.
210 ALeft-hand front and right-hand front door lock switch (cutaway).
Inverter (cutaway).
Connector (stripped chassis).
37.5 APower mirror switch (cutaway).
Not used (stripped chassis).
420 A2021: Trailer brake control.
520 ANot used (spare).
610 ANot used (spare).
710 ANot used (spare).
810 ANot used (spare).
910 A / 5 ANot used (spare).
10—Not used.
11—Not used.
127.5 ASmart datalink connector.
Enterprise wired-in-device (2021).
137.5 ACluster.
Steering column control module.
1415 ANot used (spare).
1515 ANot used (spare).
16—Not used.
177.5 ANot used.
187.5 A2021: Climate mode switch.
from 2022: R/S feed for Front blend actuator/climate mode switch (cutaway). R/S feed to strip chassis connector (stripped chassis).
195 ARadio transceiver module and telematics control unit.
205 AIgnition switch.
215 ANot used.
225 ABody builder B-pillar connector (cutaway).
Not used (stripped chassis).
2330 ANot used (spare).
2430 ANot used (spare).
2520 ANot used (spare).
2630 ANot used (spare).
2730 ANot used (spare).
2830 ANot used (spare).
2915 AUpfitter interface module (cutaway).
Not used (stripped chassis).
305 ANot used (spare).
3110 ASmart datalink connector.
3220 ARadio.
33—Not used.
3430 ANot used (spare).
355 ATow haul switch.
3615 ARearview mirror (cutaway).
Rearview camera (cutaway) (2021).
Camera lane departure (cutaway) (from 2022).
Not used (stripped chassis).
3720 ANot used (spare).
3830 ARear window switches and motors (cutaway).
Not used (stripped chassis).

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Engine Compartment

Assignment of the fuses in the engine compartment (2021-2025)

№RatingProtected Component
120 AHorn.
250 ABlower motor.
3—Not used.
430 AStarter relay.
520 ANot used (spare).
620 AUpfitter relay 4 (cutaway).
Not used (spare) (stripped chassis).
8—Not used.
10—Not used.
1220 APower point 4.
1310 AYaw sensor (stripped chassis).
Not used (spare) (cutaway).
1410 AForward looking radar (cutaway).
Not used (spare) (stripped chassis).
15—Not used.
16—Not used.
1710 APowertrain control module run/start feed.
1810 AAnti-lock brake system run/start feed.
19—Not used.
2030 AWiper power.
21—Not used.
2210 AWiper module (stripped chassis).
Not used (spare) (cutaway).
23—Not used.
2440 ABody control module – run power in feed 2.
2550 ABody control module – run power in feed 1.
26—Not used.
2720 ABody builder frame connector.
28—Not used.
2910 AB+ power 12 V(special order vehicle).
3030 APower driver seat (cutaway).
Not used (spare) (stripped chassis).
31—Not used.
3220 AVehicle power 1.
3320 AVehicle power 2.
3410 AVehicle power 3.
3520 AVehicle power 4.
36—Not used.
37—Not used.
3810 AWasher relay (stripped chassis).
Not used (spare) (cutaway).
39—Not used.
4130 ATrailer brake control connector.
4330 AInstrument panel connector (stripped chassis).
Not used (spare) (cutaway).
45—Not used.
4610 AA/C clutch.
4740 AUpfitter relay 1 (cutaway).
Not used (spare) (stripped chassis).
48—Not used.
4930 APump electronics module.
5015 AInjectors.
5120 APower point 1.
5250 AAux AC Prep on B-pillar vehicle connector (cutaway).
Not used (spare) (stripped chassis).
Power at all times (PAAT)
5330 ATrailer tow park lamps.
5440 AUpfitter 2 relay (cutaway).
Not used (spare) (stripped chassis).
R/S feed on instrument panel connector (from 2022).
5520 AUpfitter 3 relay (cutaway).
Not used (spare) (stripped chassis).
5620 APower point 2 prep B-pillar connector.
585 AUSB smart charger.
5910 APark lamps 1 (special order vehicle).
60—Not used.
61—Not used.
62—Not used.
63—Not used.
64—Not used.
65—Not used.
66—Not used.
67—Not used.
69—Not used.
7040 AInverter.
7130 AAnti-lock brake system valves.
7210 ABrake on and off switch.
73—Not used.
74—Not used.
75—Not used.
7660 AAnti-lock brake system pump.
7730 AVoltage quality module power – body control module.
7810 ATrailer tow stop lamps.
79—Not used.
8010 ATrailer tow backup lamps.
81—Not used.
825 ARun/start fuse – upfitter relays (cutaway) (2021).
B+ fuse – upfitter relay (2021).
Upfitter switch (factory location for ignition power) (from 2022)
835 A2022: Upfitter switch (optional location for power at all times).
84—Not used.
85—Not used.
86—Not used.
87—Not used.
88—Not used.
89—Not used.
9140 AHot at all times (HAAT) / B+PWR on B-Pillar connector (cutaway).
Battery Power on instrument panel connector (stripped chassis).
9310 APark lamps 3 (special order vehicle).
9410 APark lamps 2 (special order vehicle).
9520 AStop lamp relay.
96—Not used.
9750 AEngine.
B-pillar vehicle connector.
Instrument panel.
9830 ATrailer tow battery charge.
9940 A2021: Instrument panel connector.
from 2022: Upfitter 2 relay (cutaway) / Not used (spare) (stripped chassis).
100—Not used.
101—Not used.
102—Not used.
103—Not used.
104—Not used.
10515 ATrailer tow right-hand and left-hand stop and direction indicator relay power.
R02—Powertrain control module.
Power relay.
R05—Not used.

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