MB CLS-Class (C219) | 2003-2010

The first-generation Mercedes-Benz CLS-Class (C219), produced from 2003 to 2010, introduced the world to the concept of the four-door luxury coupe. With its sleek styling, refined interior, and a selection of powerful engines—including AMG variants—the C219 blended performance with sophistication in a way few sedans had done before.

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In this article, you will find fuse box diagrams for the Mercedes-Benz CLS-Class, covering models CLS280, CLS300, CLS320, CLS350, CLS500, CLS55 AMG, and CLS63 AMG for the years 2003, 2004, 2005, 2006, 2007, 2008, 2009, and 2010. These diagrams will help you understand the complete fuse layout, including the function and location of each fuse and relay within the vehicle.

What’s Included in This Guide:

  • Fuse Box Diagrams – Detailed illustrations showing the arrangement of fuses, relays, and circuit breakers.
  • Fuse Panel Locations – Information on where to find the fuse panels inside your vehicle, such as in the cabin, engine bay, and luggage compartment.
  • Fuse Assignments – A complete breakdown of what each fuse and relay controls, helping with electrical diagnostics and maintenance.

Whether you’re troubleshooting an electrical issue, replacing a blown fuse, or simply getting familiar with your CLS’s electrical system, this guide offers everything you need to keep your vehicle’s systems running smoothly.

Keep your Mercedes-Benz CLS-Class (C219, 2003–2010) in top condition with this essential fuse box, fuse panel, and relay reference guide.

The cigar lighter (power outlet) fuses in the Mercedes-Benz CLS-Class are:

  • Luggage Compartment Fuse Box:
    • Fuse â„–12: Luggage Compartment Socket
    • Fuse â„–13: Interior Socket
  • Engine Compartment Fuse Box:
    • Fuses â„–54a and â„–54b: Cigar Lighters

Instrument Panel Fuse Box

Fuse box location

The fuse box is located on the left side of the instrument panel, behind the cover.

The location of the fuses in the passenger compartment: Mercedes-Benz CLS-Class (W219; 2004-2010)

Fuse box diagram

Instrument panel fuse box diagram: Mercedes-Benz CLS-Class (2004-2010)

Assignment of the fuses in the instrument panel

Fuse Data
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â„–Fused functionAmp
21Right rear door control unit30
22Right front door control unit30
23Passenger-side front seat adjustment control unit with memory30
24Rear module Keyless Go control unit
Left rear door Keyless Go control unit
Right rear door Keyless Go control unit		25
25Stationary heater (STH) unit20
25Additionally fused via polyswitch fuse for stationary heater: STH radio remote control receiver5
26CD changer7.5
27Spare–
28Radio15
28Radio control panel and navigation unit
COMAND operating, display and controller unit		5
29Steering column module
Rotary light switch
EIS [EZS] control unit		7.5
30Data link connector7.5
31Upper control panel control unit
Cutoff relay for interruptible loads (up to 2007)		5
32Left rear door control unit30
33Left front door control unit30
34Driver-side front seat adjustment control unit, with memory30
35WSS (Weight Sensing System) control unit5
36HS [SIH] and seat ventilation control unit
Right SAM control unit		25
37AIRmatic with ADS control unit15
38NECK-PRO head restraints relay7.5
39Lower control panel control unit5
40HS [SIH] and seat ventilation control unit10
41Central gateway control unit5
42ME-SFI [ME] control unit
Driver-side SAM control unit with fuse and relay module		7.5

Luggage Compartment Fuse Box

Fuse box location

It is located on the left side of the luggage compartment, behind the cover.

The location of the fuses in the trunk: Mercedes-Benz CLS-Class (W219; 2004-2010)

Fuse box diagram

Trunk fuse box diagram: Mercedes-Benz CLS-Class (2004-2010)

Assignment of the fuses and relay in the trunk

Fuse Data
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â„–Fused functionAmp
1Front passenger partially-adjustment switch
Driver partially-electric seat adjustment switch (as of 2007)
Driver-side front seat adjustment control unit, with memory		30
2Driver partially-electric seat adjustment switch
Front passenger partially-electric seat adjustment switch (as of 2007)
Passenger-side front seat adjustment control unit with memory		30
3TPM [RDK] (tire pressure monitor) control unit
PTS (Parktronic) control unit
Navigation processor
TV combination tuner (analog/digital)		7.5
4Except engine 156.983 (CLS 55 AMG) and engine 272.985 : The fuel pump is fused via the fuel pump relay20
4Valid for engine 113.990 (CLS 55 AMG): The charge air cooler circulation pump is fused via the charge air cooler circulation pump relay7.5
5Spare relay 2–
6Audio gateway control unit40
7Rear wiper relay15
8Left antenna amplifier module
Alarm horn
Alarm signal horn with additional battery
ATA [EDW] inclination sensor		7.5
9Overhead control panel control unit25
10Heated rear window40
11–20
12USA version: Luggage compartment socket15
13Interior socket15
14–5
15Fuel filler flap CL [ZV] motor10
16HS [SIH] and seat ventilation control unit20
17–20
18–20
19Multicontour seat pneumatic pump20
20Rear window roller blind relay7.5
Relays
AFuel pump relay (except 113.990 (CLS 55 AMG), 156.983 (CLS 63 AMG), 272.985)
Charge air cooler circulation pump relay (113.990 (CLS 55AMG))
WRelay 2, terminal 15R
CSpare relay 2
DSpare
EHeated rear window relay
FRelay 1, terminal 15R
GFuel filler cap polarity reverser relay 1
HFuel filler cap polarity reverser relay 2

Engine Compartment Fuse Box

Fuse box location

The fuse box is located in the engine compartment (left-side)

The location of the fuses in the engine compartment: Mercedes-Benz CLS-Class (2004-2010)

Fuse box diagram

Under-hood fuse box diagram: Mercedes-Benz CLS-Class (2004-2010)

Assignment of the fuses and relay in the engine compartment

Fuse Data
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â„–Fused functionAmp
43Valid for M156, M272, M273:
ME-SFI [ME] control unit
Rear SAM control unit with fuse and relay module
Valid for M642:
CDI control unit
Rear SAM control unit with fuse and relay module
Valid for M113:
ME-SFI [ME] control unit
Rear SAM control unit with fuse and relay module
Fuel pump relay
Air injection relay		15
44Valid for M642: CDI control unit15
45AIRmatic with ADS control unit7.5
46Automatic 5-speed transmission (NAG): ETC [EGS] control unit
7-speed automatic transmission: Electric controller unit (VGS)		7.5
47ESP control unit5
48Restraint systems control unit7.5
49Left front reversible emergency tensioning retractor (as of 2007)
Right front reversible emergency tensioning retractor (as of 2007)
Restraint systems control unit (up to 2007)
Front passenger seat occupied and child seat recognition sensor (up to 2007)
NECK-PRO head restraints relay (2006)		7.5
50VICS power supply separation point5
51–5
52Glove compartment illumination with switch
Instrument cluster
Rotary light switch
Bi-xenon headlamp unit: Headlamp range adjustment control unit		7.5
53aFanfare horn relay15
53bFanfare horn relay15
54aIlluminated cigar lighter15
54bIlluminated cigar lighter15
55VICS power supply separation point7.5
56Wiper motor40
57Valid for M156, M272, M273:
ME-SFI [ME] control unit
Rear SAM control unit with fuse and relay module
Valid for engine M642:
CDI control unit
Rear SAM control unit with fuse and relay module		25
58Purge control valve (up to 2007)
Valid for engine 272: AAC with integrated control additional fan motor (up to 2007)
USA version:
Activated charcoal canister shutoff valve (up to 2007)
Activated charcoal filter shutoff valve (up to 2007)
Valid for engine 642: CDI control unit (2006)
Valid for engine M113, M156, M272, M273:
Cylinder 1 ignition coil
Cylinder 2 ignition coil
Cylinder 3 ignition coil
Cylinder 4 ignition coil
Cylinder 5 ignition coil
Cylinder 6 ignition coil
Cylinder 7 ignition coil
Cylinder 8 ignition coil
Valid for engine M113:
Left O2 sensor downstream TWC [KAT]
Right O2 sensor downstream TWC [KAT]		15
59Starter relay15
60Valid for engine 113.990 (CLS 55 AMG), 156.983 (CLS 63 AMG): Oil cooler fan10
61Electric air pump40
62Backup relay30
63–15
64Rotary light switch
Comfort automatic air conditioning control and operating unit
Instrument cluster (up to 2007)
AAC [KLA] control and operating unit (up to 2007)		7.5
65EIS [EZS] control unit
Electric steering lock control unit		20
66Valid for left-hand drive vehicles: Right front lamp unit
Valid for right-hand drive vehicles: Left front lamp unit
Bi-xenon headlamp unit: HRA power module		7.5
67Stop light switch10
Relays
ITerminal 87 relay, engine
KTerminal 87 relay, chassis
LStarter relay
MBackup relay
NTerminal 15 relay
OFanfare horn relay
PTerminal 15R relay
RAir pump relay (except engine 113.990 (CLS 55 AMG) and 156.983 (CLS 63 AMG))
Oil cooler fan relay (only engine 113.990 (CLS 55 AMG) and 156.983 (CLS 63 AMG))
SAIRmatic relay (semi-active air suspension)

Front Pre-Fuse Box

Front Pre-Fuse Box (location): Mercedes-Benz CLS-Class (2004-2010)
Front Pre-Fuse Box (diagram): Mercedes-Benz CLS-Class (2004-2010)

Front Pre-Fuse Box

Fuse Data
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â„–Fused functionAmp
68PTC heater booster (as of 1.6.06)200
69–150
70Additional battery relay (up to 31.5.06)150
71AAC with integrated control additional fan motor150
72SBC hydraulic unit (up to 31.5.06)
ESP control unit (as of 1.6.06)		50
73SBC hydraulic unit (up to 31.5.06)
ESP control unit (as of 1.6.06)		40
74AIRmatic relay40
75Right SAM control unit40
76Right front reversible emergency tensioning retractor (as of 1.6.06)40
77Heating systems recirculation unit40

Rear Pre-fuse Box

Rear Pre-fuse Box (location): Mercedes-Benz CLS-Class (2004-2010)

Remove/install:

Disconnect battery ground cable
Unclip latching hook (1) and remove rear prefuse box (F33)       
Unclip fuse holder (2) at the rear prefuse box(F33)
Detach electrical connector (3) on the rear prefuse box (F33)
Detach supply lines (red) (4) on the rear prefuse box (F33), mark and put the supply line (red) (4) to one side
Unscrew positive lead (black) (6) on the rear prefuse box (F33) and remove positive lead (black) (6)

Install in the reverse order

Rear Pre-fuse Box (diagram): Mercedes-Benz CLS-Class (2004-2010)

Rear Pre-fuse Box

Fuse Data
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â„–Fused functionAmp
78Driver-side SAM control unit with fuse and relay module200
79Rear SAM control unit with fuse and relay module200
80Driver SAMcontrol unit with fuse and relay module150
81Interior fuse box150
82AMG vehicles: FP fuse (F82A), Air injection fuse (F82B)150
F82ALeft fuel pump control unit
Right fuel pump control unit		30
F82BAir injection relay40
83–30
84Battery sensor (as of 2007)
Battery control unit (up to 2007)		5
85Voice control system (VCS [SBS]) control unit
Universal Portable CTEL Interface (UPCI [UHI]) control unit
Japan version:
GPS box control unit
Microphone array control unit
USA version:
CTEL [TEL] compensator, data
E-net compensator		5
86USA version: SDAR control unit (up to 2007)5
87Pneumatic pump for dynamic seat control30
88TLC [HDS] control unit30
89–40
90Left front reversible emergency tensioning retractor (as of 2007)40
91Valid with engine 272.985: Fuel pump control unit (as of 2007)30

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