Access Mercedes-Benz S-Class fuse box diagrams for 2021–2025 models with fuse locations, panel layouts, and detailed electrical information for all variants. This article covers the seventh-generation Mercedes-Benz S-Class (Model Code: W223), available from 2021, and includes fuse box diagrams for Mercedes-Benz S450, S480, S500, S580, S680, S350d, S400d, S450d and S63 (2021, 2022, 2023, 2024 and 2025), along with details about the location of the fuse panels inside the vehicle and a clear explanation of the assignment of each fuse (fuse layout).
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The fuse box in the engine compartment is positioned on the right side of the engine bay, under the plastic cover by the windshield/cowl area. To open it: Release the rotary catches on cover (1), then lift the cover up and off. Remove screws (2) and swing out bar (3). Remove screws (4), then take the fuse box lid (5) off to the side.
Fuse Box Diagram
Fuses
Assignment of the fuses in the engine compartment
Fuse Data
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Automatic transmission, Voltage stabilising capacitor (Li-lon battery)
143
20A
Engine/transmission/HV battery cooling (AMG)
144
10A
DRIVE PILOT
145
—
–
146
30A / 40A
30A: Engine/transmission/HV battery cooling (AMG) 40A: ABS / ASR / ESP / BAS / Electrical parking brake
147
5A / 30A
5A: ABS / ASR / ESP / BAS / Electrical parking brake (Except AMG) 30A: Engine/transmission/HV battery cooling (AMG)
Dashboard
Fuse Box Location
The fuse box is positioned behind the dashboard’s driver-side panel and can be reached with the driver’s door open. To access the fuses, open cover (1) in the arrow’s direction and remove it.
Fuse Box Diagram
Fuses
Assignment of the fuses in the passenger compartment (Dashboard)
Fuse Data
Full access is available to registered users — log in or register.
HV battery management system / Hybrid power electronics, Hybrid service disconnect
203
7.5A
Telephone systems
204
10A
Engine electronics
205
7.5A
360 degree view camera/reversing camera
206
7.5A
Dynamic driving seat, Seat adjustment/seat climate control – front
207
—
–
208
7.5A
DRIVE PILOT
209
30A
Central control unit – front
210
10A
48V battery management system, HV battery management system / Hybrid power electronics, On-board battery charger plug-in
211
30A
Door operating functions – front left (LL), Door operating functions – front right (RL), Front window lifters, Special equipment for special protection (Guard)
212
30A
Luxury seat heating – front
213
30A
Left belt tensioner – front (LL), Right belt tensioner – front (RL)
214
30A
Door operating functions – rear left (RL), Power window – rear (RL)
A/C system / heater, Climate control control panel – front
227
—
–
228
5A
COMAND
229
5A
Telephone systems
230
5A
ETC/Electronic Toll Collect
231
—
–
232
—
–
Passenger Footwell
Fuse Box Location
The fuse box is situated in the front passenger footwell, behind the small access panel on the side of the lower dashboard/center console. To reach the fuses, open cover (1) in the direction indicated by the arrow, then remove it.
Fuse Box Diagram
Fuses
Assignment of the fuses in the front passenger footwell
Fuse Data
Full access is available to registered users — log in or register.
Reading lamps – rear, Roof lamps, Sun visor mirror lighting
321
—
–
322
7.5A
Dynamic driving seat, Seat adjustment/seat climate control – front
323
10A
DISTRONIC PLUS, Driving assistance system
324
7.5A
Driving assistance system
325
7.5A
Telephone systems
326
30A
Door operating functions – front left (RL), Door operating functions – front right (LL), Front window lifters, Special equipment for special protection (Guard)
327
30A
Seat adjustment/seat climate control – front
328
30A
Door operating functions – rear left (LL), Power window- rear (LL)
329
30A
Left belt tensioner- front (RL), Right belt tensioner- front (LL)
330
7.5A / 20A
7.5A: USB interface 20A: USB Package Plus
331
30A
COMAND
332
30A
Luxury seat heating – front
333
30A
Panoramic glass roof (MAGIC SKY CONTROL) Sliding sunroof, Roller blind f. sliding sunroof/Panoramic glass roof, Special equipment for special protection (Guard)
334
30A
Panoramic glass roof (MAGIC SKY CONTROL) Sliding sunroof, Roller blind f. sliding sunroof/Panoramic glass roof, Special equipment for special protection (Guard)
335
30A
AMG DYNAMIC SELECT
Luggage Compartment
Fuse Box Location
The fuse box is positioned beneath the cover on the right side of the luggage compartment. To reach the fuses, fold cover (1) down in the direction indicated by the arrow.
Fuse Box Diagram
Fuses
Assignment of the fuses in the luggage compartment
Fuse Data
Full access is available to registered users — log in or register.