MB S-Class (W223) | 2021-2025

Access Mercedes-Benz S-Class fuse box diagrams for 2021–2025 models with fuse locations, panel layouts, and detailed electrical information for all variants. This article covers the seventh-generation Mercedes-Benz S-Class (Model Code: W223), available from 2021, and includes fuse box diagrams for Mercedes-Benz S450, S480, S500, S580, S680, S350d, S400d, S450d and S63 (2021, 2022, 2023, 2024 and 2025), along with details about the location of the fuse panels inside the vehicle and a clear explanation of the assignment of each fuse (fuse layout).

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Engine Compartment

Fuse Box Location

The fuse box in the engine compartment is positioned on the right side of the engine bay, under the plastic cover by the windshield/cowl area. To open it: Release the rotary catches on cover (1), then lift the cover up and off. Remove screws (2) and swing out bar (3). Remove screws (4), then take the fuse box lid (5) off to the side.

Fuse Box Diagram

Fuses

Assignment of the fuses in the engine compartment

Fuse Data
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No.AmpsDescription
10015A / 25A15A: Engine/transmission/HV battery cooling
25A: Engine/transmission/HV battery cooling (AMG)
1017.5A / 15APetrol: Engine electronics (7.5A)
Diesel: Engine electronics (15A)
10220A / 25A20A: Engine electronics (12-cyl. petrol), Engine electronics (4/6-cyl. petrol)
25A: Engine electronics (6-cyl. diesel), Engine electronics (8-cyl. petrol)
10315A / 20A / 25A15A: Engine electronics (4/6-cyl. petrol), Engine electronics (6-cyl. diesel), Secondary air injection pump
20A: Engine electronics (12-cyl. petrol), Engine electronics (8-cyl. petrol), Secondary air injection pump
25A: Engine electronics (48V 6-cyl. diesel), Secondary air injection pump
10415A / 20A15A: Engine electronics (4/6-cyl. petrol), Engine electronics (6-cyl. diesel)
20A: Engine electronics (12-cyl. petrol), Engine electronics (8-cyl. petrol)
10515A / 20A15A: Engine electronics (12-cyl. petrol), Engine electronics (4/6-cyl. petrol), Engine electronics (6-cyl. diesel)
20A: Engine electronics (8-cyl. petrol)
106
10725ALamps – front
10830AWindscreen wipers
1097.5AA/C system / heater, Inductive charging (high-voltage)
11010AA/C system / heater
11130ACentral control unit – front
11230AWindshield wiper recess heater
11325ALamps – front
11430ACentral control unit – front
1155AABS / ASR / ESP / BAS / Electrical parking brake, Gimbal reading lamp
11620AAdditional fuses for special-purpose vehicle
11730A / 40A30A: Starter motor 12 V
40A: Starter motor 12 V (6 Cyl. Hybrid)
1187.5AEngine electronics, Engine/transmission/HV battery cooling, Haptic accelerator pedal module
11910AElectrical exhaust flap, Engine electronics, HV battery management system / Hybrid power electronics
12010AEngine electronics
12115AEngine/transmission/HV battery cooling
1225AEngine electronics
12310ADRIVE PILOT (AMG)
1247.5AStarter motor 12 V
125
126
127
1285AABS / ASR / ESP / BAS / Electrical parking brake
1295ACentral control unit – front
130
131
132
133
134
135
13640ASecondary air injection pump
137
138
1395AEngine electronics
1405A48V battery management system, AMG DYNAMIC SELECT, AMG Performance 4MATIC, Engine electronics
1417.5AEngine electronics (48V) (6-cyl. diesel)
14210AAutomatic transmission, Voltage stabilising capacitor (Li-lon battery)
14320AEngine/transmission/HV battery cooling (AMG)
14410ADRIVE PILOT
145
14630A / 40A30A: Engine/transmission/HV battery cooling (AMG)
40A: ABS / ASR / ESP / BAS / Electrical parking brake
1475A / 30A5A: ABS / ASR / ESP / BAS / Electrical parking brake (Except AMG)
30A: Engine/transmission/HV battery cooling (AMG)

Dashboard

Fuse Box Location

The fuse box is positioned behind the dashboard’s driver-side panel and can be reached with the driver’s door open. To access the fuses, open cover (1) in the arrow’s direction and remove it.

Fuse Box Diagram

Fuses

Assignment of the fuses in the passenger compartment (Dashboard)

Fuse Data
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No.AmpsDescription
20010ADiagnostic socket
2015ACOMAND
2025AHV battery management system / Hybrid power electronics, Hybrid service disconnect
2037.5ATelephone systems
20410AEngine electronics
2057.5A360 degree view camera/reversing camera
2067.5ADynamic driving seat, Seat adjustment/seat climate control – front
207
2087.5ADRIVE PILOT
20930ACentral control unit – front
21010A48V battery management system, HV battery management system / Hybrid power electronics, On-board battery charger plug-in
21130ADoor operating functions – front left (LL), Door operating functions – front right (RL), Front window lifters, Special equipment for special protection (Guard)
21230ALuxury seat heating – front
21330ALeft belt tensioner – front (LL), Right belt tensioner – front (RL)
21430ADoor operating functions – rear left (RL), Power window – rear (RL)
21530ASeat adjustment/seat climate control – front
21625AAir suspension, E-ACTIVE BODY CONTROL
217
21815ASteering wheel heating/steering wheel adjustment
2195A / 7.5A5A: Head-Up Display (Entry)
7.5A: Head-Up Display (High)
2207.5APerfume atomiser
221
222
22310ACOMAND
22410AInstrument cluster
2257.5ACOMAND
2265AA/C system / heater, Climate control control panel – front
227
2285ACOMAND
2295ATelephone systems
2305AETC/Electronic Toll Collect
231
232

Passenger Footwell

Fuse Box Location

The fuse box is situated in the front passenger footwell, behind the small access panel on the side of the lower dashboard/center console. To reach the fuses, open cover (1) in the direction indicated by the arrow, then remove it.

Fuse Box Diagram

Fuses

Assignment of the fuses in the front passenger footwell

Fuse Data
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No.AmpsDescription
300
30115AAdditional fuses for special-purpose vehicle, Special equipment for special protection (Guard)
3025AAnti-theft alarm system
3035AAuxiliary heating, COMAND, DRIVE PILOT, Emergency call system, Parking Assist, Telephone systems
30410ABackup battery, Ignition lock, KEYLESS-GO
3055AAnti-theft alarm system
306Light/rain sensor
307A/C system / heater- rear, Climate control panel – rear
308HV battery management system / Hybrid power electronics, Starter motor 48V
309Tyre pressure monitor
31048V battery management system
311Backup battery, Ignition lock
312CAR 2X COMMUNICATION
313Airbag systems
314A/C system / heater- rear, Climate control panel – rear
315Auxiliary heating
316
317AMG DYNAMIC SELECT
3187.5AAirbag systems
3197.5AAMG Performance 4MATIC, Automatic transmission, Backup battery, Ignition lock, KEYLESS-GO
32010AReading lamps – rear, Roof lamps, Sun visor mirror lighting
321
3227.5ADynamic driving seat, Seat adjustment/seat climate control – front
32310ADISTRONIC PLUS, Driving assistance system
3247.5ADriving assistance system
3257.5ATelephone systems
32630ADoor operating functions – front left (RL), Door operating functions – front right (LL), Front window lifters, Special equipment for special protection (Guard)
32730ASeat adjustment/seat climate control – front
32830ADoor operating functions – rear left (LL), Power window- rear (LL)
32930ALeft belt tensioner- front (RL), Right belt tensioner- front (LL)
3307.5A / 20A7.5A: USB interface
20A: USB Package Plus
33130ACOMAND
33230ALuxury seat heating – front
33330APanoramic glass roof (MAGIC SKY CONTROL) Sliding sunroof, Roller blind f. sliding sunroof/Panoramic glass roof, Special equipment for special protection (Guard)
33430APanoramic glass roof (MAGIC SKY CONTROL) Sliding sunroof, Roller blind f. sliding sunroof/Panoramic glass roof, Special equipment for special protection (Guard)
33530AAMG DYNAMIC SELECT

Luggage Compartment

Fuse Box Location

The fuse box is positioned beneath the cover on the right side of the luggage compartment. To reach the fuses, fold cover (1) down in the direction indicated by the arrow.

Fuse Box Diagram

Fuses

Assignment of the fuses in the luggage compartment

Fuse Data
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No.AmpsDescription
400
4017.5A / 20A7.5A: USB interface
20A: USB Package Plus
40215ARefrigerator box
40315A12 V power socket, centre console, Cigar lighter, centre console
40415AEngine Order Cancellation (EOC) / Road Noise Cancellation (RNC), Power socket in the boot
40515ACigar lighter – front
406
4075ACOMAND
4087.5APreparation Rear Seat Entertainment, Rear Seat Entertainment System
4095ATelephone systems
4105AFront contactless gesture control
4115AAdaptive lighting in the rear
41210A115 V/230 V socket in the rear, Thermo cupholder
41320AAuxiliary heating
41430ACentral control unit – rear
41525AFuel system
41630ADoor operating functions – rear right, Power window – rear
41730ADynamic driving seat
41840ABlueTEC, Rear axle steering (AMG)
41950AHeated rear window
42040AHigh-end sound system, Sound system
42130ACentral control unit – rear
42225A115 V/230 V socket in the rear
42330AAMG: Engine Order Cancellation (EOC) / Road Noise Cancellation (RNC)
42430AIndividual luxury seats, seat heating – rear, Rear bench seat, seat heating
42520AUSB Package Plus
42630ARemote boot lid closing/opening
427
428
429
43015AHV battery management system / Hybrid power electronics
4317.5ACommunication module, Emergency call system
4327.5ADriving assistance system
43310AAMG DYNAMIC SELECT
434
435
4365ATelephone systems
4377.5AAmbient lighting
4387.5AParking Assist
4397.5ADriving assistance system
44015AA/C system / heater – rear
4415ARemote boot lid closing/opening
4425ABlueTEC
443
444
4457.5ATelephone systems
4467.5AHybrid sound generator
44740AHigh-end sound system
448
449
45030ARear seat belt extenders, Seat adjustment/seat climate control – rear
45130ARear seat belt extenders, Seat adjustment/seat climate control – rear
45230AIndividual luxury seats, seat heating – rear
45315AOn-board battery charger plug-in
4547.5ADynamic driving seat
4557.5ADynamic driving seat
456
45720AAMG Performance 4MATIC
45830AFront/rear heated armrest
45930ASound system subwoofer
460
461
462
463
464
4655ATelephone systems
46615ARear Seat Entertainment System
467
468
4697.5ADRIVE PILOT
470
47115A / 20A15A: Panic alarm system control unit / special signal system
20A: Panic alarm system control unit / Trailer coupling
47225AMultifunction control unit for special-purpose vehicle
47325AMultifunction control unit for special-purpose vehicle
47430AAdditional fuses for special-purpose vehicle, Trailer coupling
47520A / 30A20A: Trailer coupling
30A: Special equipment for special protection (Guard)
47630ASpecial equipment for special protection (Guard), Trailer coupling
4777.5AThermo cupholder
47815A / 30A15A: Panic alarm system control unit / special signal system
30A: Panic alarm system control unit / Trailer coupling
479
480
48120A / 25A25A: Convenience rear doors
20A: Special equipment for special protection (Guard)
48220A / 25A25A: Convenience rear doors
20A: Special equipment for special protection (Guard)

Luggage Compartment (Additional)

Fuse Box Diagram

Fuses

Assignment of the fuses in the luggage compartment (Additional fuse holder)

Fuse Data
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No.AmpsDescription
1
27.5ADRIVE PILOT
37.5ADRIVE PILOT
45ADRIVE PILOT
5
6

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